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Panama Canal Cruises from the UK

Find the best cruise through the Panama Canal from the UK for you in 2026, 2027 and 2028 with CruiseKings below. Call one of our Cruise Experts on 0800 197 8050 to book your dream no-fly cruise holiday today!

Panama Canal Cruises from UK

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    Southampton, UK to Los Angeles, CA

    Cunard

    Queen Victoria 10 January 2027 26 nights

    Itinerary: Southampton - New York - Oranjestad - Puerto Vallarta - Los Angeles

    • FREE up to $1000 On Board Spend per couple - When Booking Cunard Fare
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £2,739pp
    • Ocean View £3,179pp
    • Balcony £4,159pp
    • Suite £11,269pp

    Includes extra savings of up to £230pp

    more details

    Southampton to San Francisco

    P&O Cruises

    Arcadia 06 January 2028 24 nights

    Itinerary: Southampton - Gran Canaria - Barbados - Oranjestad - Manzanillo - San Diego - San Francisco

    • Adult Only
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £339pp Deposit
    • No Tipping Required

    Sail From UK from

    • Interior Call Us
    • Ocean View £3,379pp
    • Balcony £4,339pp

    Includes extra savings of up to £44pp

    more details

    Southampton to Sydney

    P&O Cruises

    Arcadia 06 January 2028 48 nights

    Itinerary: Southampton - Gran Canaria - Barbados - Oranjestad - Manzanillo - San Diego - San Francisco - Honolulu - Nawiliwili - Apia...

    • Adult Only
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Indian Ocean Cruises from UK
    • No Tipping Required

    Sail From UK from

    • Interior Call Us
    • Ocean View £6,969pp
    • Balcony £8,409pp

    Includes extra savings of up to £85pp

    more details

    Southampton to Cape Town

    P&O Cruises

    Arcadia 06 January 2028 106 nights

    Itinerary: Southampton - Gran Canaria - Barbados - Oranjestad - Manzanillo - San Diego - San Francisco - Honolulu - Nawiliwili - Apia...

    • Adult Only
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Indian Ocean Cruises from UK
    • No Tipping Required

    Sail From UK from

    Call us now on 0800 197 8050

    more details

    Southampton to Singapore

    P&O Cruises

    Arcadia 06 January 2028 85 nights

    Itinerary: Southampton - Gran Canaria - Barbados - Oranjestad - Manzanillo - San Diego - San Francisco - Honolulu - Nawiliwili - Apia...

    • Adult Only
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Indian Ocean Cruises from UK
    • No Tipping Required

    Sail From UK from

    Call us now on 0800 197 8050

    more details

    Southampton to Hong Kong

    P&O Cruises

    Arcadia 06 January 2028 75 nights

    Itinerary: Southampton - Gran Canaria - Barbados - Oranjestad - Manzanillo - San Diego - San Francisco - Honolulu - Nawiliwili - Apia...

    • Adult Only
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Indian Ocean Cruises from UK
    • No Tipping Required

    Sail From UK from

    Call us now on 0800 197 8050

    more details

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